{"product_id":"bpc157","title":"BPC157","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eBPC-157 is a synthetic research peptide comprising 15 amino acids with a unique non-natural sequence. BPC-157 peptide has garnered significant research interest for its cytoprotective and regenerative properties in preclinical models. This BPC157 pentadecapeptide demonstrates broad-spectrum efficacy in studies of gastrointestinal, musculoskeletal, neural, and vascular injury, making it a versatile tool for tissue repair research.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eBPC-157 exerts its pharmacological effects through multiple interconnected pathways. It promotes healing by boosting growth factors and reducing inflammatory cytokines. A key mechanism involves activation of the nitric oxide (NO) system, enhancing endothelial nitric oxide synthase (eNOS) phosphorylation through the Src-Caveolin-1-eNOS pathway, which is associated with tissue repair and angiogenesis. BPC-157 also stimulates nitric oxide synthase generation and possesses free radical scavenging activity. Recent research has established a novel molecular mechanism centered on the BPC-157-FBXO22-BACH1 axis: intracellular BPC-157 engages the E3 ubiquitin ligase adaptor protein FBXO22, suppressing ubiquitination and proteasomal degradation of the transcription factor BACH1, thereby enhancing vascular endothelial cell proliferation and tube-forming capacity.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue Regeneration:\u003c\/strong\u003e Investigated for promoting repair of muscles, tendons, ligaments, bones, and soft tissues, with improved functional, structural, and biomechanical outcomes in preclinical models.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Health:\u003c\/strong\u003e Studied for mucosal protection, wound healing, inflammatory bowel disease, and mitigation of NSAID-induced injury.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAngiogenesis Studies:\u003c\/strong\u003e Employed to evaluate the formation of new blood vessels through the BPC-157-FBXO22-BACH1 axis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIschemia-Reperfusion Injury:\u003c\/strong\u003e Used in preclinical models to assess protective effects against skeletal muscle I\/R injury by attenuating oxidative stress, modulating apoptosis, and reducing inflammation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammatory Modulation:\u003c\/strong\u003e Utilized to evaluate reduction of inflammatory cytokines and immune regulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 137525-51-0 (free base); acetate salt: 1628202-19-6\u003cbr\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 9941957\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₆₂H₉₈N₁₆O₂₂\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1,419.5 g\/mol\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 98% (batch-dependent; refer to Certificate of Analysis)\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Freely soluble in water and DMSO; prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"yuansensetech","offers":[{"title":"BC 5mg","offer_id":52038356435234,"sku":"BC5","price":56.0,"currency_code":"USD","in_stock":true},{"title":"BC 10mg","offer_id":52038356468002,"sku":"BC10","price":100.0,"currency_code":"USD","in_stock":true},{"title":"BC 20mg","offer_id":52070509314338,"sku":"BC20","price":140.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/BPC157.jpg?v=1783741740","url":"https:\/\/yuansensepeptide.com\/products\/bpc157","provider":"Yuansensetech™","version":"1.0","type":"link"}