{"product_id":"cjc-1295-without-dac","title":"CJC-1295 Without DAC","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails class=\"peptide-details\" open=\"\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eCJC-1295 without DAC (also known as Modified GRF 1-29, CJC-1295-no DAC, or GHRH 1-29-NH2) is a synthetic 30-amino acid peptide analogue of growth hormone-releasing hormone (GHRH). Unlike the DAC (Drug Affinity Complex) version, this peptide does not contain a lysine-based linker that enables binding to serum albumin. As a result, CJC-1295 without DAC has a shorter half-life and promotes a more physiologic, pulsatile release of growth hormone, aligning with the body's natural secretory pattern. The compound is widely studied in endocrinology research as a tool for investigating the growth hormone axis.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eCJC-1295 without DAC acts as a potent agonist of the growth hormone-releasing hormone receptor (GHRH-R) in the pituitary gland. Upon receptor binding, it stimulates the synthesis and pulsatile secretion of growth hormone (GH), which in turn elevates circulating levels of insulin-like growth factor 1 (IGF-1). The absence of the DAC moiety results in a shorter duration of action compared to the DAC-conjugated version, allowing for more targeted study of acute GH release dynamics without the sustained \"GH bleed\" associated with long-acting analogues.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eEndocrinology and GH-Axis Research:\u003c\/strong\u003e Employed as a research tool to study the complex interactions between GHRH stimulation, GH secretion, and downstream physiological outcomes.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic Studies:\u003c\/strong\u003e Investigated for its role in lipid metabolism, including potential effects on fat reduction and metabolic regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscle and Recovery Research:\u003c\/strong\u003e Studied in preclinical models for its potential to support muscle function, particularly in combination with other growth hormone secretagogues.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombination Studies:\u003c\/strong\u003e Frequently utilized alongside GHRP (Growth Hormone Releasing Peptides) such as Ipamorelin to evaluate synergistic effects on the GH axis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\" open=\"\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 863288-34-0 (acetate salt); also reported as 446036-97-1 (free base)\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₁₅₂H₂₅₂N₄₄O₄₂\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 3,367.9 g\/mol\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99% \u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in sterile water and DMSO; prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"yuansensetech","offers":[{"title":"CND 5mg","offer_id":52038353256738,"sku":"CND5","price":108.0,"currency_code":"USD","in_stock":true},{"title":"CND 10mg","offer_id":52038353289506,"sku":"CND10","price":186.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/CJC-1295WhitoutDAC.jpg?v=1783741685","url":"https:\/\/yuansensepeptide.com\/products\/cjc-1295-without-dac","provider":"Yuansensetech™","version":"1.0","type":"link"}