{"product_id":"ghrp-6-acetate","title":"GHRP-6 Acetate","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails open=\"\" class=\"peptide-details\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cdiv\u003eGHRP-6 is a synthetic research peptide, a hexapeptide with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2. GHRP-6 peptide belongs to the growth hormone secretagogue family and functions as a structural mimic of ghrelin, the endogenous ligand for the growth hormone secretagogue receptor. This Synthetic hexapeptide was first described in 1984 and has been extensively studied for its potent GH-releasing activity in multiple species.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eGHRP-6 exerts its effects by selectively binding to and activating the growth hormone secretagogue receptor type 1a (GHS-R1a), a Class A G protein-coupled receptor (GPCR) expressed primarily in the hypothalamus and pituitary gland. Upon receptor activation, GHRP-6 stimulates intracellular signaling cascades involving phospholipase C (PLC) activation, inositol phosphate production, and intracellular calcium mobilization. This signaling pathway promotes the synthesis and pulsatile release of growth hormone from somatotroph cells in the anterior pituitary, independent of the cAMP pathway utilized by GHRH. Unlike native ghrelin, GHRP-6 also acts as a negative allosteric modulator of ghrelin signaling. The compound stimulates GH release in a specific and dose-related manner, with activity observed even after oral administration.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth Hormone Axis Research:\u003c\/strong\u003e Employed as a selective tool to study GHSR signaling, GH secretion dynamics, and the physiological regulation of the hypothalamic-pituitary-somatotropic axis.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic and Appetite Studies:\u003c\/strong\u003e Investigated for its role in food intake regulation, energy homeostasis, and metabolic research.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGastrointestinal Motility Research:\u003c\/strong\u003e Studied for its effects on gastrointestinal smooth muscle contractility and cholinergic responses.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMuscle and Body Composition Studies:\u003c\/strong\u003e Explored for its potential to stimulate lean muscle mass and influence protein deposition.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 87616-84-0 (free base); 145177-42-0 (acetate salt)\u003cbr\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 9919153\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₄₆H₅₆N₁₂O₆ (free base); C₄₆H₅₆N₁₂O₆ · 3C₂H₄O₂ (acetate salt)\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 873.01 g\/mol (free base); 1,053.19 g\/mol (acetate salt)\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂ (HwAWfK-NH₂)\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99%\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e Lyophilized powder\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in sterile water and DMSO; prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e","brand":"yuansensetech","offers":[{"title":"G6 5mg","offer_id":52038353715490,"sku":"G65","price":40.0,"currency_code":"USD","in_stock":true},{"title":"G6 10mg","offer_id":52038353748258,"sku":"G610","price":70.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/GHRP-6Acetate.jpg?v=1783741694","url":"https:\/\/yuansensepeptide.com\/products\/ghrp-6-acetate","provider":"Yuansensetech™","version":"1.0","type":"link"}