{"product_id":"lipo-c-b12","title":"LIPO-C B12","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails open=\"\" class=\"peptide-details\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eLIPO-C (with B12) is a research-grade compounded lipotropic formulation supplied in a sterile liquid solution for laboratory and scientific research applications. The formulation combines lipotropic agents—methionine, inositol, and choline (MIC)—with L-carnitine, cyanocobalamin (Vitamin B12), and additional cofactors that support hepatic fat metabolism, methylation pathways, and cellular energy production. This complete formulation is designed for controlled in vitro studies and biochemical compound analysis requiring B12 supplementation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eLIPO-C exerts its effects through the synergistic action of its core components on hepatic lipid metabolism and cellular energy pathways. Methionine serves as a methyl donor, converting to S-adenosylmethionine (SAMe) in hepatocytes, which is required for phosphatidylcholine synthesis—the structural backbone of VLDL particles that package triglycerides for export from the liver. Choline directly supports phosphatidylcholine production through the CDP-choline pathway, providing a redundant mechanism that remains functional even in patients with MTHFR polymorphisms affecting SAMe synthesis. Inositol functions as a secondary messenger in insulin receptor signaling, modulating glucose uptake and reducing insulin resistance. L-Carnitine supports fatty-acid transport into mitochondria for β-oxidation. Vitamin B12 (cyanocobalamin) acts as a cofactor for methionine synthase, facilitating the remethylation of homocysteine to methionine, thereby supporting the methylation cycle and enhancing the lipotropic effects. The mechanism is hepatocentric—preventing hepatic triglyceride accumulation rather than triggering systemic lipolysis in adipose tissue.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eHepatic Lipid Metabolism:\u003c\/strong\u003e Investigated for studying hepatic fat processing, VLDL export, and lipid clearance mechanisms with B12-mediated methylation support.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMethylation Pathway Research:\u003c\/strong\u003e Employed to evaluate methyl donor utilization, SAMe synthesis, and homocysteine metabolism in the presence of B12 cofactor.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInsulin Signaling and Glucose Metabolism:\u003c\/strong\u003e Studied for inositol-mediated modulation of insulin receptor signaling and glucose uptake.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMitochondrial Fatty Acid Oxidation:\u003c\/strong\u003e Utilized to assess L-carnitine-mediated fatty-acid transport and mitochondrial energy production.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCombination Therapy Research:\u003c\/strong\u003e Explored in conjunction with GLP-1 receptor agonists to evaluate complementary pathways in appetite signaling and fat mobilization.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\" open=\"\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e Sterile liquid solution (with B12)\u003cbr\u003e\u003cstrong\u003eCore Components:\u003c\/strong\u003e Methionine, Inositol, Choline (MIC complex)\u003cbr\u003e\u003cstrong\u003eAdditional Components:\u003c\/strong\u003e Vitamin B12 (cyanocobalamin), L-Carnitine, Pyridoxine (B6)\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99%\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Supplied as sterile liquid solution; prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e","brand":"yuansensetech","offers":[{"title":"LC216  10mg","offer_id":52038353420578,"sku":"LC216","price":104.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/LIPO-CB12.jpg?v=1783741687","url":"https:\/\/yuansensepeptide.com\/products\/lipo-c-b12","provider":"Yuansensetech™","version":"1.0","type":"link"}