{"product_id":"pt-141","title":"PT-141","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails open=\"\" class=\"peptide-details\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cdiv\u003ePT-141 is a synthetic research peptide, a cyclic heptapeptide analogue of α-melanocyte-stimulating hormone (α-MSH) derived from Melanotan II. PT-141 peptide functions as a non-selective melanocortin receptor agonist, originally developed for research into sexual dysfunction and hemorrhagic shock. This Synthetic peptide received FDA approval in 2019 for treatment of hypoactive sexual desire disorder in premenopausal women.\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003ePT-141 exerts its effects by binding to and activating multiple melanocortin receptors, including MC1R, MC3R, MC4R, and MC5R, which are expressed primarily in the central nervous system. Its potency order is MC1R \u0026gt; MC4R \u0026gt; MC3R \u0026gt; MC5R \u0026gt; MC2R. Activation of MC4R in hypothalamic and limbic brain regions increases dopamine release and modulates pathways associated with sexual desire and arousal.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSexual Dysfunction Research:\u003c\/strong\u003e Investigated for the treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women and erectile dysfunction in men.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeuroendocrinology:\u003c\/strong\u003e Employed as a tool to study melanocortin receptor signaling, dopamine release, and central nervous system pathways regulating sexual behavior.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHemorrhagic Shock and Reperfusion Injury:\u003c\/strong\u003e Studied for its potential protective effects in preclinical models.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 189691-06-3 (free base); 1607799-13-2 (acetate salt)\u003cbr\u003e\u003cstrong\u003ePubChem CID:\u003c\/strong\u003e 9941379 (free base); 91971505 (acetate salt)\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₅₀H₆₈N₁₄O₁₀ (free base); C₅₂H₇₂N₁₄O₁₂ (acetate salt)\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 1,025.18 g\/mol (free base); 1,085.22 g\/mol (acetate salt)\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 98% (batch-dependent; refer to Certificate of Analysis)\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e White to off-white lyophilized powder\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in sterile water (≥100 µg\/mL), DMSO, and PBS (pH 7.2); prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"yuansensetech","offers":[{"title":"P41 10mg","offer_id":52038355517730,"sku":"P41","price":93.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/PT-141.jpg?v=1783741720","url":"https:\/\/yuansensepeptide.com\/products\/pt-141","provider":"Yuansensetech™","version":"1.0","type":"link"}