{"product_id":"tb500-thymosin-b4-acetate","title":"TB500 (Thymosin B4 Acetate）","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails open=\"\" class=\"peptide-details\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eTB-500 is a synthetic research peptide derived from thymosin beta-4 (Tβ4), a highly conserved 43-amino acid protein found in human and animal tissues. TB-500 peptide corresponds to the N-terminal acetylated fragment (Ac-LKKTETQ) of thymosin beta 4, representing the active site responsible for actin binding, cell migration, and wound healing. This Thymosin Beta 4 fragment is widely studied for its roles in tissue repair, angiogenesis, and inflammation regulation.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eTB-500 exerts its biological effects primarily through actin cytoskeleton dynamics. It functions as a G-actin (globular actin) sequestering protein, regulating actin polymerization—a process essential for cell motility, structure, and division. This mechanism triggers a cascade of downstream effects including enhanced cell migration, angiogenesis (formation of new blood vessels), and attenuation of inflammatory responses. TB-500 also promotes endothelial cell differentiation, keratinocyte migration, and collagen deposition, while demonstrating anti-fibrotic properties through modulation of the Akt signaling pathway.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTissue Repair and Regeneration:\u003c\/strong\u003e Investigated for promoting repair of muscles, tendons, ligaments, skin, and heart tissue.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAngiogenesis Studies:\u003c\/strong\u003e Employed to evaluate new blood vessel formation through upregulation of vascular endothelial growth factor (VEGF) expression.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eWound Healing:\u003c\/strong\u003e Studied for enhancing keratinocyte migration, collagen deposition, and dermal tissue repair.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eInflammatory Modulation:\u003c\/strong\u003e Used in preclinical models to assess reduction of inflammation and immune regulation.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 885340-08-9\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₃₈H₆₈N₁₀O₁₄\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e 889.01 g\/mol\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 98% (batch-dependent; refer to Certificate of Analysis)\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e White to off-white lyophilized powder\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in sterile water and DMSO; prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"yuansensetech","offers":[{"title":"TB 5mg","offer_id":52038354665762,"sku":"TB5","price":114.0,"currency_code":"USD","in_stock":true},{"title":"TB 10mg","offer_id":52038354698530,"sku":"TB10","price":222.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/TB500.jpg?v=1783741711","url":"https:\/\/yuansensepeptide.com\/products\/tb500-thymosin-b4-acetate","provider":"Yuansensetech™","version":"1.0","type":"link"}