{"product_id":"tesamorelin-tesa","title":"Tesamorelin (Tesa)","description":"\u003cstyle\u003e\n.peptide-details {\n  border: 1px solid #8A97B5;\n  margin-bottom: 8px;\n  border-radius: 8px;\n  overflow: hidden;\n}\n.peptide-details summary {\n  cursor: pointer;\n  padding: 12px 16px;\n  font-weight: bold;\n  list-style: none;\n  display: flex;\n  align-items: center;\n  justify-content: space-between;\n}\n.peptide-details summary::-webkit-details-marker {\n  display: none;\n}\n.peptide-details summary::after {\n  content: '';\n  display: inline-block;\n  width: 8px;\n  height: 8px;\n  border-right: 1px solid #8A97B5;\n  border-bottom: 1px solid #8A97B5;\n  transform: rotate(45deg);\n  transition: transform 0.2s ease;\n  flex-shrink: 0;\n  margin-left: 10px;\n}\n.peptide-details[open] summary::after {\n  transform: rotate(-135deg);\n}\n.peptide-details .peptide-content {\n  padding: 16px;\n}\n\u003c\/style\u003e\n\u003ch3 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\"\u003eProduct Description\u003c\/h3\u003e\n\u003cdetails class=\"peptide-details\" open=\"\"\u003e\n\u003csummary\u003eOverview\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eTesamorelin (also known as Tesa) is a synthetic research peptide, a stabilized analogue of human growth hormone-releasing hormone (GHRH). Tesamorelin peptide consists of the full 44-amino acid GHRH sequence with a trans-3-hexenoic acid modification at the N-terminal tyrosine for enhanced stability. This TESA peptide is classified as a GHRH analog and somatotropin agonist, FDA-approved for reduction of excess abdominal fat in HIV-infected patients with lipodystrophy and widely studied for growth hormone dynamics and metabolism research.\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eMechanism of Action\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003eTesamorelin binds to the growth hormone-releasing hormone receptor (GHRH-R) on somatotroph cells in the anterior pituitary gland, mimicking the action of endogenous GHRH. This receptor binding stimulates the synthesis and pulsatile release of endogenous growth hormone (GH), which in turn elevates circulating levels of insulin-like growth factor 1 (IGF-1). Through this mechanism, tesamorelin promotes metabolic effects including reduction of visceral adipose tissue (VAT), improvement of lipid profiles, and maintenance of glucose homeostasis.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eResearch Applications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eMetabolic and Body Composition Studies:\u003c\/strong\u003e Investigated for its effects on visceral fat reduction, lean body mass, and lipid metabolism.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGrowth Hormone Axis Research:\u003c\/strong\u003e Employed as a research tool to study GHRH receptor signaling, GH secretion dynamics, and IGF-1 regulation.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHIV-Associated Lipodystrophy:\u003c\/strong\u003e Studied for the treatment of excess abdominal fat in HIV-infected patients with lipodystrophy.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNeurocognitive Research:\u003c\/strong\u003e Explored for potential effects on neurocognitive impairment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e\n\u003cdetails class=\"peptide-details\"\u003e\n\u003csummary\u003eProduct Specifications\u003c\/summary\u003e\n\u003cdiv class=\"peptide-content\"\u003e\n\u003cp\u003e\u003cstrong\u003eCAS Number:\u003c\/strong\u003e 218949-48-5\u003cbr\u003e\u003cstrong\u003eMolecular Formula:\u003c\/strong\u003e C₂₂₁H₃₆₆N₇₂O₆₇S\u003cbr\u003e\u003cstrong\u003eMolecular Weight:\u003c\/strong\u003e ~5,135.8–5,195.9 g\/mol\u003cbr\u003e\u003cstrong\u003eSequence:\u003c\/strong\u003e YADAIFTNSYRKVLGQLSARKLLQDIMSRQQGESNQERGARARL\u003cbr\u003e\u003cstrong\u003ePurity:\u003c\/strong\u003e ≥ 99% (batch-dependent; refer to Certificate of Analysis)\u003cbr\u003e\u003cstrong\u003eForm:\u003c\/strong\u003e White to off-white lyophilized powder\u003cbr\u003e\u003cstrong\u003eStorage:\u003c\/strong\u003e Store at ≤ -20°C in a cool, dry place, protected from light and moisture\u003cbr\u003e\u003cstrong\u003eSolubility:\u003c\/strong\u003e Soluble in sterile water and DMSO; prepare working solutions per laboratory protocol\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/details\u003e","brand":"yuansensetech","offers":[{"title":"TSM 5mg","offer_id":52038354534690,"sku":"TSM5","price":154.0,"currency_code":"USD","in_stock":true},{"title":"TSM 10mg","offer_id":52038354567458,"sku":"TSM10","price":292.0,"currency_code":"USD","in_stock":true},{"title":"TSM 15mg","offer_id":52038354600226,"sku":"TSM15","price":406.0,"currency_code":"USD","in_stock":true},{"title":"TSM 20mg","offer_id":52038354632994,"sku":"TSM20","price":504.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1008\/2805\/3794\/files\/Tesa.jpg?v=1783741709","url":"https:\/\/yuansensepeptide.com\/products\/tesamorelin-tesa","provider":"Yuansensetech™","version":"1.0","type":"link"}