CJC-1295 (without DAC)+IPA

CJC-1295 without DAC+IPA is a research peptide blend combining CJC-1295 without DAC and Ipamorelin in a single lyophilized vial. CP10 delivers a synergistic combination of CJC-1295 without DAC (5 mg) and Ipamorelin (5 mg), two growth hormone secretagogues designed to support experimental studies of GH axis modulation and metabolic regulation. This CJC-1295 without DAC+IPA formulation targets complementary receptor pathways — CJC-1295 (Modified GRF 1-29) provides pulsatile GH release via GHRH receptors, while Ipamorelin acts as a selective agonist of the ghrelin/GHSR pathway.

CP10 exerts its effects through simultaneous activation of two distinct receptor pathways involved in growth hormone regulation. CJC-1295 without DAC acts as a potent agonist of the growth hormone-releasing hormone receptor (GHRH-R) in the pituitary gland, stimulating the synthesis and pulsatile secretion of growth hormone (GH). Ipamorelin selectively binds to the ghrelin/growth hormone secretagogue receptor (GHSR), promoting GH release through a complementary mechanism. The absence of the DAC moiety in CJC-1295 results in a shorter duration of action, allowing for more targeted study of acute GH release dynamics. This dual-pathway approach creates a synergistic effect, with each peptide targeting a different receptor to amplify the growth hormone pulse.

• Growth Hormone Axis Research: Employed as a research tool to study the complex interactions between GHRH stimulation, GHSR activation, and GH secretion dynamics.
• Metabolic Studies: Investigated for its role in lipid metabolism, including potential effects on fat reduction and metabolic regulation.
• Muscle and Recovery Research: Studied in preclinical models for its potential to support muscle function and recovery, particularly in combination with other growth hormone secretagogues.
• Endocrinology: Utilized to evaluate pulsatile GH secretion patterns and the physiological effects of growth hormone modulation.

Peptide Content: CJC-1295 without DAC (5 mg), Ipamorelin (5 mg) per vial
CAS Number: 863288-34-0 (CJC-1295 without DAC acetate salt); 170851-70-4 (Ipamorelin)
Molecular Formula: C₁₅₂H₂₅₂N₄₄O₄₂ (CJC-1295 without DAC); C₃₈H₄₉N₉O₅ (Ipamorelin)
Molecular Weight: 3,367.9 g/mol (CJC-1295 without DAC); 711.85 g/mol (Ipamorelin)
Sequence: H-Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂ (CJC-1295 without DAC); Aib-His-D-2-Nal-D-Phe-Lys-NH₂ (Ipamorelin)
Purity: ≥ 98% (batch-dependent; refer to Certificate of Analysis)
Form: Lyophilized powder
Storage: Store at ≤ -20°C in a cool, dry place, protected from light and moisture
Solubility: Soluble in sterile water and DMSO; prepare working solutions per laboratory protocol