• Selank COA151057
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yuansensetech

Selank

Selank

$58.00
$58.00
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Dosage

Product Description

Overview
Selank is a synthetic research peptide with the amino acid sequence Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). Selank peptide is a stabilized analogue of tuftsin, an endogenous immunomodulatory tetrapeptide, extended with three natural L-amino acids to enhance metabolic stability and prolong duration of action. Developed by the Institute of Molecular Genetics of the Russian Academy of Sciences, this Selank heptapeptide is classified as a neuropsychotropic agent with demonstrated anxiolytic and nootropic properties.
Mechanism of Action

Selank exerts its effects through multiple interconnected mechanisms, including GABAergic modulation, inhibition of enkephalin-degrading enzymes, upregulation of BDNF expression, monoamine neurotransmitter modulation, and immunomodulation through cytokine gene expression and interferon release.

Research Applications
  • Anxiety and Stress Research: Investigated for its pronounced anxiolytic (anti-anxiety) and antistress effects, without the sedative, amnestic, or addictive properties associated with traditional anxiolytics like benzodiazepines.
  • Cognitive Enhancement and Nootropic Studies: Employed in research to evaluate its positive influence on memory formation and learning processes.
  • Immunomodulation and Antiviral Research: Studied for its ability to modulate the immune system and for its demonstrated antiviral activity against various viruses including influenza A (H3N2), herpes simplex virus (HSV-1 and HSV-2), and cytomegalovirus (CMV).
  • Neurodegenerative Disease Models: Used in preclinical models to investigate its potential neuroprotective effects in conditions involving cognitive decline and neuronal damage.
Product Specifications

CAS Number: 129954-34-3
Molecular Formula: C₃₃H₅₇N₁₁O₉
Molecular Weight: 751.9 g/mol
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP)
Purity: ≥ 98% (batch-dependent; refer to Certificate of Analysis)
Form: White to off-white lyophilized powder
Storage: Store at ≤ -20°C in a cool, dry place, protected from light and moisture
Solubility: Soluble in sterile water and DMSO; prepare working solutions per laboratory protocol

 

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Research Use Only

This product is intended for research purposes only and is not for human consumption, therapeutic use, or diagnostic applications. Please ensure compliance with all applicable regulations and institutional guidelines.